Sickle Cell Retinopathy is a common condition among persons with sickle cell disease. In SS and SC, about 14% and 43% of patients have sickle cell retinopathy respectively. Advanced sickle cell retinopathy can cause blindness from bleeding inside the eye or retinal detachment. It is therefore important for persons with sickle cell disease to have comprehensive examination of the eye, including a dilated examination of the retina to identify early stages of sickle cell retinopathy every 1 to 2 years. This should start from the age of 10 years.